Francisco Pereira was always connected to the public works sector. Between 1975 and 1980, he served as President of the Autonomous Roads Board of Mozambique and directed the elaboration of the Development Plan for the Mozambique Road Network.
Between 1980 and 1988, he served as National Director of Economy and Construction at the Ministry of Construction and Water.
Between 1988 and 1995, he was hired as a consultant to the World Bank.
In 1999, he returned to the road sector, first as Vice-President of the National Road Administration and then in 2004, with the creation of the Roads Fund he was appointed Chairman of the Board of Directors of the Roads Fund.
In 2005, he was elected President of the General Assembly of the Order of Engineers of Mozambique, and was re-elected in 2010, until 2015
Between 2010 and 2104, he served as Deputy Minister of Public Works and Housing of the Government of Mozambique.